Product Name :
PPP3CC Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
calcineurin A gamma antibody CALCINEURIN A3 antibody Calcineurin antibody Calcineurin testis specific catalytic subunit antibody Calmodulin dependent calcineurin A subunit gamma isoform antibody Calmodulin-dependent calcineurin A subunit gamma isoform antibody CALNA3 antibody CAM PRP catalytic subunit antibody CAM-PRP catalytic subunit antibody CNA3 antibody 展开
Function :
Serine/threonine-protein phosphatase 2B catalytic subunit gamma isoform (PP2BC) is an enzyme that in humans is encoded by the PPP3CC gene. Calmodulin-dependent protein phosphatase, calcineurin, is involved in a wide range of biologic activities, acting as a Ca(2+)-dependent modifier of phosphorylation status. In testis, the motility of the sperm is thought to be controlled by cAMP-dependent phosphorylation and a unique form of calcineurin appears to be associated with the flagellum. The calcineurin holoenzyme is composed of catalytic and regulatory subunits of 60 and 18 kD, respectively. At least 3 genes, calcineurin A-alpha (CALNA1; MIM 114105), calcineurin A-beta (CALNA2; MIM 114106), and calcineurin A-gamma (CALNA3), have been cloned for the catalytic subunit. These genes have been identified in humans, mice, and rats, and are highly conserved between species (90 to 95% amino acid identity).
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human PPP3CC 51-150/512
Species reactivity:
Human, Mouse, Rat, Dog, Pig, Cow, Horse, Rabbit, Sheep
Verify application:
WB, ELISA, IHC-P, IF, ICC
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.Tetrabutylammonium periodate web Avoid repeated freeze/thaw cycles.Potassium osmate dihydrate site The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.PMID:33593208 When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
58 KDa
Positive control :
Testis.