Product Name :
TrkA Recombinant Rabbit Monoclonal Antibody [SU0354]
Predicted band size :
88 kDa
Observed band size :
140 kDa
Synonyms:
gp140trk antibody High affinity nerve growth factor receptor antibody High affinity nerve growth factor receptor precursor antibody MTC antibody Neurotrophic tyrosine kinase receptor type 1 antibody NTRK1 antibody NTRK1_HUMAN antibody Oncogene TRK antibody p14-TrkA antibody p140 TrkA antibody 展开
Function :
Tropomyosin receptor kinase A (TrkA), also known as high affinity nerve growth factor receptor, neurotrophic tyrosine kinase receptor type 1, or TRK1-transforming tyrosine kinase protein. This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself (autophosphorylation) and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes.5-Amino-1H-1,2,4-triazole-3-carboxamide custom synthesis Mutations in this gene have been associated with congenital insensitivity to pain with anhidrosis, self-mutilating behaviors, intellectual disability and/or cognitive impairment and certain cancers.Formula of 2-(3-Methyl-3H-diazirin-3-yl)ethan-1-ol
Antibody Type:
Recombinant Rabbit monoclonal Antibody
Immunogen :
Synthetic peptide within Human TrkA aa 747-796 / 796.PMID:33411471
Species reactivity:
Human, Mouse, Rat
Verify application:
WB, IF-Cell, IF-Tissue, IHC-P, IP, FC
Coupling :
unconjugated
Clone number:
SU0354
RRID:
AB_3069805
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at +4℃ after thawing. Aliquot store at -20℃ or -80℃. Avoid repeated freeze / thaw cycles.
Storage buffer solution:
1*TBS (pH7.4), 0.05% BSA, 40% Glycerol. Preservative: 0.05% Sodium Azide.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
Predicted band size: 88 kDa
Positive control :
TF-1 cell lysate, mouse brain tissue lysate, rat brain tissue lysate, Hela, N2A, SH-SY5Y, mouse liver tissue, mouse kidney tissue, human tonsil tissue.