Product Name :
Nmnat1 Rabbit Polyclonal Antibody
Predicted band size :
Observed band size :
Synonyms:
EC 2.7.7.1 antibody LCA9 antibody Leber’s congenital amaurosis 9 antibody NaMN adenylyltransferase 1 antibody nicotinamide nucleotide adenylyltransferase 1 antibody Nicotinamide-nucleotide adenylyltransferase 1 antibody Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 antibody nicotinate nucleotide adenylyltransferase 1 antibody Nicotinate-nucleotide adenylyltransferase 1 antibody NMN adenylyltransferase 1 antibody 展开
Function :
Catalyzes the formation of NAD(+) from nicotinamide mononucleotide (NMN) and ATP. Can also use the deamidated form; nicotinic acid mononucleotide (NaMN) as substrate with the same efficiency. Can use triazofurin monophosphate (TrMP) as substrate. Also catalyzes the reverse reaction, i.e. the pyrophosphorolytic cleavage of NAD(+). For the pyrophosphorolytic activity, prefers NAD(+) and NAAD as substrates and degrades NADH, nicotinic acid adenine dinucleotide phosphate (NHD) and nicotinamide guanine dinucleotide (NGD) less effectively. Fails to cleave phosphorylated dinucleotides NADP(+), NADPH and NAADP(+). Protects against axonal degeneration following mechanical or toxic insults.
Antibody Type:
Rabbit Polyclonal Antibody
Immunogen :
KLH conjugated synthetic peptide derived from human Nmnat1 201-279/279
Species reactivity:
Human, Mouse, Rat, Chicken, Dog, Cow, Rabbit, Sheep
Verify application:
WB, ELISA
Coupling :
unconjugated
Clone number:
RRID:
Form :
Liquid
Concentration :
1ug/ul
Storage instructions:
Store at -20℃ for one year.Buy4,4′,4”,4”’-Methanetetrayltetraaniline Avoid repeated freeze/thaw cycles.Thalidomide 5-fluoride In stock The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20℃.PMID:33412940 When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4℃.
Storage buffer solution:
0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol.
Subtype:
IgG
Purification method :
Protein A affinity purified.
ELTSA :
Molecular weight :
32 KDa
Positive control :
Widely expressed with highest levels in skeletal muscle, heart and kidney. Also expressed in the liver pancreas and placenta. Widely expressed throughout the brain.